Cholesterol / Generic Lipitor

What is lipitor(atorvastatin)?

• Lipitor is an HMG CoA reductase inhibitor. Lipitor blocks the production of cholesterol (a type of fat) in the body.
• Lipitor is used to reduce the amounts of LDL (bad) cholesterol, total cholesterol, triglycerides (another type of fat), and apolipoprotein B (a protein needed to make cholesterol) in your blood. Lipitor is also used to increase the level of HDL (good) cholesterol in your blood. These actions are important in reducing the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.
• Lipitor may also be used for purposes other than those listed in this medication guide.

What should I discuss with my doctor before taking lipitor?

• Do not take lipitor without first talking to your doctor if you have liver disease.
• Before taking lipitor, tell your doctor if you
  • drink alcoholic beverages,
  • have a chronic muscular disease,
  • require major surgery, or
  • have a blood disorder.
• You may not be able to take lipitor, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Lipitor is in the FDA pregnancy category X. This means that lipitor is known to cause birth defects if it is taken during pregnancy. Do not take lipitor if you are pregnant or could become pregnant during treatment.
• It is not known whether lipitor passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take lipitor?

• Take lipitor exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Lipitor can be taken with or without food.
• Lipitor is usually taken once a day. Try to take your dose at the same time each day. Follow your doctor's instructions.
• Your doctor may want to monitor your liver function with blood tests before starting treatment with lipitor, at twelve weeks after both the start of your treatment and any increase in dose, and periodically (every 6 months) thereafter. Depending on the results of these tests, your doctor can determine how much monitoring you will require.
• Grapefruit and grapefruit juice may interact with lipitor. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
• Eat a low-fat, low-cholesterol diet. To realize beneficial effects from lipitor, avoid fatty, high-cholesterol foods.
• It is important to take lipitor regularly to get the most benefit.
• Do not stop taking lipitor without first talking to your doctor. Lipitor may need to be taken on a long-term basis for the treatment of high cholesterol.
• Your doctor may want you to have blood tests or other medical evaluations during treatment with lipitor to monitor progress and side effects.
• Store lipitor at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

• Seek emergency medical attention if an overdose is suspected.
• The symptoms of an lipitor overdose are not known.

What should I avoid while taking lipitor?

• Alcohol and lipitor can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined.
• Grapefruit and grapefruit juice may interact with lipitor. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

What are the possible side effects of lipitor?

• Rare cases of muscle problems and liver problems have been associated with the use of lipitor and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes, abdominal pain, unexplained fatigue, dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems.
• If you experience any of the following serious side effects, stop taking lipitor and seek emergency medical attention or contact your doctor immediately:
  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • decreased urine or rust-colored urine; or
  • blurred vision.
• Other, less serious side effects may be more likely to occur. Continue to take lipitor and talk to your doctor if you experience
  • headache;
  • upset stomach or flatulence; or
  • a rash.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What drug(s) may interact with lipitor?

• alcohol-containing beverages
• antacids
• barbiturates (examples: phenobarbital, butalbital, primidone)
• birth control pills
• bosentan
• carbamazepine
• certain antibiotics such as clarithromycin, erythromycin, or troleandomycin
• colestipol
• cyclosporine
• diltiazem
• fenofibrate
• gemfibrozil
• grapefruit juice
• herbal medicines such as St. John's Wort or Went Yeast/Red Rice Yeast
• imatinib, STI-571
• medicines for fungal infections (examples: fluconazole, itraconazole, ketoconazole, voriconazole)
• medicines for treating HIV infection
• niacin
• nefazodone
• oxcarbazepine
• phenytoin
• pioglitazone
• rifampin, rifabutin, or rifapentine
• telithromycin
• verapamil